# Bad first reaction

**URL:** <https://oozingyellowcrusts.com/t/bad-first-reaction/178>\
**Category:** Treatments\
**Created:** [October 24, 2016, 7:02pm UTC](https://oozingyellowcrusts.com/t/bad-first-reaction/178 "2016-10-24T19:02:33Z")\
**Posts on this page:** 1\
**Showing post:** 2

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**Author:** ![Tso](https://oozingyellowcrusts.com/letter_avatar_proxy/v4/letter/t/e8c25b/32.png) [@Tso](https://oozingyellowcrusts.com/u/Tso)\
**Post date:** [October 24, 2016, 10:48pm UTC](https://oozingyellowcrusts.com/t/bad-first-reaction/178/2 "2016-10-24T22:48:54Z")

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People often report an initial worsening when starting with Soolantra. For some the skin can somewhat more red and irritated than that. It’s unclear whether this is a temporary worsening before it gets better, or incompatible skin with Soolantra. Although, if I’m correct, all people here on this forum have success with Soolantra. But on the Rosacea Group froum, there may be people to stopped because of it.

Take for example:

> [@Demodex "die-off"](http://oozingyellowcrusts.com/t/demodex-die-off/93):
>
> Would anyone like to share their personal experience with die-off symptoms after using Soolantra or another Ivermectin treatment? I feel I am currently experiencing this die-off reaction but I can’t be sure if that’s what it is or if it is just my skin reacting badly to the treatment. My symptoms are small red circles all over my face after treatment. They do not form any real oozing lesions. It just looks red and irritated.

@Dm78 she also mentions “red circles”.

And then, within 2 weeks:

> [@Demodex "die-off"](http://oozingyellowcrusts.com/t/demodex-die-off/93/8):
>
> Misfit I am seeing great results! I wish I had the nerve to post my photos I took over the last two weeks. Drastic change. I had a lot of red weird irritated areas. No real oz zing. Just what I call “angry” skin. It’s gotten much better now. However I was a little let down this morning when I developed a small oozer on my chin. But I attribute it to being lazy with my ivermectin formula. From what I have read it seems it is best to keep on with it religiously for quite some time. Just how lo…

And now:  
[http://oozingyellowcrusts.com/t/does-yours-spread/171/3?u=tso](http://oozingyellowcrusts.com/t/does-yours-spread/171/3)

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You could try this:

- Reduce frequency of application. You could temporary stop, give the skin some rest before continuing again. For example, instead of applying it every day, apply in once per 3 days.
- Apply less Soolantra per application.
- Reduce concentration of ivermectin by adding a moisturizer after applying Soolantra. Or maybe even a bit before applying Soolantra.

Personally, I didn’t get red circles, but my skin did got a bit redder and new small lessions appeared, although they didn’t really ooze.

I would be interested in seeing a photo of a red circle and the severness of it, because I’m not sure what to visualize from it.

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