From day one, it stopped me from having lesions. In addition, I've tightened up my diet to no dairy, no grains. Overall, I feel better on no dairy/no grains but it does not affect my skin breaking out. That means if I have a beer or eat some cheese, I don't break out (so long as I'm steady with soolantra). In 6 months, I've only had one outbreak. That was when I took a pill called Oreganol (concentrated oregano in a pill). Also, as I've begun taking apple cider vinegar once every morning, I do get small bumps that swell up and weep very slightly but nothing catastrophic.
So, I'm never quite sure whether my body is cleansing out some bad stuff or if its a reaction to ingesting things like apple cider vinegar or oregano. I think at its core, it's a lymphatic system problem. Our lymphatic system can't clean itself out so it dumps lymph fluid onto the skin. Just my weird theory.