I applied Soolantra to those areas where lesions did occur, even when there were no lesions at that moment. For me, that was almost the complete face. Basically, the green area’s of this: What does it look like? (photos) Except around the eyes, but I did apply it between the eyes and on the eyebrows. Sometimes I also did apply on the ears and on the scalp.
Soolantra seems also to be effective with a small dose. Considering the high price of Soolantra, you could moisture the face a bit with water, then apply Soolantra afterwards, so that it spreads easier over the dampened face than a dry face, thereby reducing the amount that you need. I often combined it with a moisturizer from the same company as Soolantra, which Soolantra also uses as its base ingredient. (For more info, see Skin hydration & Moisturizers ) I combined it by first applying Soolantra, then waiting 5 minutes, and then I applied the moisturizer.